制药

Being at the forefront of new drug discoveries, the pharmaceutical industry relies heavily on close support from Dow Corning to ensure that current and new drugs are made and delivered on time.

Providing unique chemical properties that protect various carboxy, amino and hydroxyl groups, silanes have been used for more than 20 years in the production of antibiotics such as penicillin and celphlasporin-type medications.  TBMS is also used in anticholestrol drug production as a " super-protector" of the active groups during synthesis.

As the global market for antibacterial compounds increases due to population growth and increasing healthcare demands, pharmaceutical manufacturers will rely on silanes as they develop the next generation of antibiotic therapies.

Silanes available for pharmaceutical manufacturing applications:

	Dow Corning® brand silane		Short Name		Protecting Group		CAS Number
	Z-1224 Trimethylchlorosilane		TMSCl		TMS		75-77-4
	TBMS (tert-butyldimethylchlorosilane)		TBSCl		TBS		18162-48-6
	TBMS-50 EA (tert-butyldimethylchlorosilane)		TBSCl in Ethyl Acetate		TBS		18162-48-6
	TBMS-50T (tert-butyldimethylchlorosilane)		TBSCl in Toluene		TBS		18162-48-6

For More Information:

• Read more about silicones in healthcare.